2-Piperidinecarboxylic acid t-butyl ester

2-Piperidinecarboxylic acid t-butyl ester - Names and Identifiers

Name	2-Piperidinecarboxylic acid T-butyl ester HCl
Synonyms	tert-Butyl 2-piperidinecarboxylate tert-butyl piperidine-2-carboxylate 2-Piperidinecarboxylic acid t-butyl ester 2-Piperidinecarboxylic acid T-butyl ester HCl 2-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL tert-butyl piperidine-2-carboxylate hydrochloride 2-Piperidinecarboxylic acid, 1,1-dimethylethyl ester 2-Piperidinecarboxylic acid T-butyl ester hydrochloride 2-piperidinecarboxylic acid tert-butyl ester hydrochloride
CAS	147202-35-5
InChI	InChI=1/C10H19NO2.ClH/c1-10(2,3)13-9(12)8-6-4-5-7-11-8;/h8,11H,4-7H2,1-3H3;1H

2-Piperidinecarboxylic acid t-butyl ester - Physico-chemical Properties

Molecular Formula	C10H19NO2
Molar Mass	185.26
Density	0.976±0.06 g/cm3(Predicted)
Boling Point	241.0±33.0 °C(Predicted)
Flash Point	122.3°C
Vapor Presure	0.00325mmHg at 25°C
pKa	8.25±0.10(Predicted)
Storage Condition	Room Temprature

2-Piperidinecarboxylic acid t-butyl ester - Introduction

2-Piperidinecarboxylic acid T-butyl ester HCl, also known as 2-piperidinate hydrochloride, is a compound in the form of its hydrochloride salt. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to pale yellow crystalline powder.
-Solubility: Soluble in water and organic solvents, such as alcohols, ethers, etc.
-Melting point: about 145-150 ℃.
-chemical formula: C13H22N2O2 · HCl.

Use:
-Pharmaceutical field: 2-piperidinecarboxylic acid tert-butyl hydrochloride is widely used as a pharmaceutical intermediate for the synthesis of anticholinesterase drugs and antipsychotic drugs, such as piperazine.
-Laboratory research: 2-piperidinecarboxylic acid tert-butyl hydrochloride is also used in organic synthesis reactions in the laboratory. It can be used as a base catalyst, phosphating reagent, esterification reagent, condensation reagent, etc.

Method:
-tert-Butyl 2-piperidinecarboxylate hydrochloride can be obtained by dissolving tert-butyl 2-piperidinecarboxylate in hydrochloric acid followed by crystallization.
-Chemical reaction: C13H22N2O2 HCl → C13H22N2O2 · HCl

Safety Information:
-2-Piperidinecarboxylic acid tert-butyl hydrochloride is an organic compound with certain risks.
-Wear appropriate protective equipment such as gloves, goggles and masks when in use.
-Avoid direct contact with skin and inhalation of its vapors.
-During storage and handling, care should be taken to avoid contact with oxidants and flammable substances to prevent fire and explosion.
-In case of contact, immediately flush the affected area with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:52